static void Main(string[] args)
        {
            string str = @"F:\test.txt";
            string[] n = File.ReadAllLines(str);
            for (int i = 0; i < n.Length; ++i)
            {
                n[i] = n[i].Trim();
            }
            string[]m = System.Text.RegularExpressions.Regex.Split(n[0], @"\s{1,}");
            string[,] A = new string[n.Length, m.Length];
            for (int i = 0; i < n.Length; ++i)
            {
                for (int j = 0; j < m.Length; ++j)
                {
                    string[] s = System.Text.RegularExpressions.Regex.Split(n[i], @"\s{1,}");
                    A[i, j] = s[j];
                }
            }
            for(int i = 0; i < n.Length; ++i)
            {
                for (int j = 0; j < m.Length; ++j)
                {
                    Console.Write(A[i, j] + ' ');
                }
                Console.WriteLine();
            }
            int[,]B=new int[n.Length, m.Length];
            for (int i = 0; i < n.Length; ++i)
            {
                for (int j = 0; j < m.Length; ++j)
                {
                    B[i, j] = int.Parse(A[i,j]);
                }
            }
            for (int i = 0; i < n.Length; ++i)
            {
                for (int j = 0; j < m.Length; ++j)
                {
                    Console.Write("{0} ",B[i,j]);
                }
                Console.WriteLine();
            }
        }

试试上面这个,亲测有效